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Beyond Basics
The Normal Digestive Processes
in the Lower GI Tract

Physiological Processes

Motility. The small intestine has two patterns of movement (motility): peristalsis and segmentation. Peristalsis is contractions that begin at a particular point and move down the small intestine for some distance. Peristalsis is the primary mechanism by which the contents of the lumen are pushed along the intestine toward the colon during the digestive process. Segmentation refers to the process in which a number of contractions occur simultaneously at uniform intervals along the intestine. This is the primary mechanism for mixing the contents of the lumen with secretions and increasing the contact between the lumenal contents and the mucosa, thereby increasing absorption.

Figure 6 – Short animation showing a comparison of peristalsis without segmentation
  
Figure 6 – Short animation showing a comparison of peristalsis with segmentation
  
Secretion. Specialized cells in the mucosa lining the small intestine produce and deliver (secrete) a variety of enzymes, mucus, and other substances into the lumen to regulate digestion. These cells can also produce substances that function like hormones, and that are secreted into the blood rather than into the lumen.
Digestion. Food must be broken down into smaller particles in order for the body to build and nourish cells and provide energy. The digestive process breaks down carbohydrates, proteins, and fats into small molecules that are capable of being absorbed by the body. This is done by chemical substances, such as pancreatic juices, and by mechanical means, such as the mixing together of nutrients and enzymes in the lumen that increases the exposure of food to digestive enzymes.
Absorption. The nutrients in the lumen come in contact with the epithelial cells and are absorbed through this cell membrane. In addition, the small intestine also absorbs water and electrolytes.

Elimination. This is the process in which waves of peristalsis move down the small intestine, pushing waste material towards the colon, where it is stored. The waste is then transported to the rectum, and eliminated through the anus.

 

This information is provided as a general educational service
and is not intended to recommend any particular treatment plan
or to replace the advice of physicians. It is important that patients
seek and rely on the advice of a healthcare professional
about their individual medical conditions.

  
  
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